Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients

Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients

Background: Cerebral metabolic rate of oxygen (CMRO2), a measure of global oxygen metabolism, reflects resting cellular activity. The mechanisms underlying fatigue and cognitive dysfunction in multiple sclerosis (MS) remain unknown. If fatigue indeed reflects ongoing autoimmune activity and cortical...

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Bibliographic Details
Main Authors: Kl. West, Dk. Sivakolundu, Gb. Maruthy, Md. Zuppichini, P. Liu, Bp. Thomas, Js. Spence, H. Lu, Dt. Okuda, B. Rypma
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Multiple Sclerosis
MRI
Fatigue
Cognition
Cerebral blood flow
Energy metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220301182

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http://www.sciencedirect.com/science/article/pii/S2213158220301182

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