Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients
Background: Cerebral metabolic rate of oxygen (CMRO2), a measure of global oxygen metabolism, reflects resting cellular activity. The mechanisms underlying fatigue and cognitive dysfunction in multiple sclerosis (MS) remain unknown. If fatigue indeed reflects ongoing autoimmune activity and cortical...
Main Authors: | Kl. West, Dk. Sivakolundu, Gb. Maruthy, Md. Zuppichini, P. Liu, Bp. Thomas, Js. Spence, H. Lu, Dt. Okuda, B. Rypma |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | NeuroImage: Clinical |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158220301182 |
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