Hypoxia and Microvascular Alterations Are Early Predictors of IDH-Mutated Anaplastic Glioma Recurrence

Hypoxia and Microvascular Alterations Are Early Predictors of IDH-Mutated Anaplastic Glioma Recurrence

Anaplastic gliomas (AG) represents aggressive brain tumors that often affect young adults. Although isocitrate-dehydrogenase (IDH) gene mutation has been identified as a more favorable prognostic factor, most IDH-mutated AG patients are confronted with tumor recurrence. Hence, increased knowledge ab...

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Bibliographic Details
Main Authors: Andreas Stadlbauer, Stefan Oberndorfer, Gertraud Heinz, Max Zimmermann, Thomas M. Kinfe, Arnd Doerfler, Michael Buchfelder, Natalia Kremenevski, Franz Marhold
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
anaplastic glioma
isocitrate-dehydrogenase
IDH gene mutation
recurrence
hypoxia
neovascularization
Online Access:https://www.mdpi.com/2072-6694/13/8/1797

Internet

https://www.mdpi.com/2072-6694/13/8/1797

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