EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells

EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells

Abstract Epigenetic deregulation remarkably triggers mechanisms associated with tumor aggressiveness like epithelial–mesenchymal transition (EMT). Since EMT is a highly complex, but also reversible event, epigenetic processes such as DNA methylation or chromatin alterations must be involved in its r...

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Bibliographic Details
Main Authors: Pablo Lindner, Sushmita Paul, Markus Eckstein, Chuanpit Hampel, Julienne K. Muenzner, Katharina Erlenbach-Wuensch, Husayn P. Ahmed, Vijayalakshmi Mahadevan, Thomas Brabletz, Arndt Hartmann, Julio Vera, Regine Schneider-Stock
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-2340-4

Internet

https://doi.org/10.1038/s41419-020-2340-4

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