Distinct Migratory Properties of M1, M2, and Resident Macrophages Are Regulated by αDβ2 and αMβ2 Integrin-Mediated Adhesion

Distinct Migratory Properties of M1, M2, and Resident Macrophages Are Regulated by αDβ2 and αMβ2 Integrin-Mediated Adhesion

Chronic inflammation is essential mechanism during the development of cardiovascular and metabolic diseases. The outcome of diseases depends on the balance between the migration/accumulation of pro-inflammatory (M1) and anti-inflammatory (M2) macrophages in damaged tissue. The mechanism of macrophag...

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Bibliographic Details
Main Authors: Kui Cui, Christopher L. Ardell, Nataly P. Podolnikova, Valentin P. Yakubenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
integrin αDβ2(CD11d/CD18)
integrin αMβ2(CD11b/CD18)
macrophages (M1/M2)
migration
inflammation
adhesive receptors
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02650/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02650/full

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