Acute-Phase Levels of CXCL8 as Risk Factor for Chronic Arthralgia Following Chikungunya Virus Infection

The immunopathogenesis of chikungunya virus (CHIKV) infection and the role of acute-phase immune response on joint pain persistence is not fully understood. We investigated the profile of serum chemokine and cytokine in CHIKV-infected patients with acute disease, compared the levels of these biomark...

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Main Authors: Leile Camila Jacob-Nascimento, Caroline Xavier Carvalho, Monaíse Madalena Oliveira Silva, Mariana Kikuti, Rosângela Oliveira Anjos, Jordana Rodrigues Barbosa Fradico, Ana Carolina Campi-Azevedo, Laura Beatriz Tauro, Gúbio Soares Campos, Patricia Sousa dos Santos Moreira, Moyra Machado Portilho, Olindo Assis Martins-Filho, Guilherme Sousa Ribeiro, Mitermayer Galvão Reis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.744183/full