Transforming growth factor beta (TGF-β) in milk: a review
Bovine milk and colostrum contain growth factors such as insulin-like growth factor IGF-I, IGF-II, transforming growth factor TGF-β1, TGF-β2, epidermal growth factor EGF, basic fibroblast growth factor bFGF and platelet-derived growth factor PDGF. In recent years, intense scientific interest has bee...
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Empresa de Pesquisa Agropecuária de Minas Gerais (EPAMIG)
2016-06-01
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doaj-e9c66d7375274ba4a66fdc56e53bb0092020-11-25T01:01:56ZengEmpresa de Pesquisa Agropecuária de Minas Gerais (EPAMIG)Revista do Instituto de Latícinios Cândido Tostes0100-36742238-64162016-06-0170422623810.14295/2238-6416.v70i4.384328Transforming growth factor beta (TGF-β) in milk: a reviewFernanda Lopes da SilvaMichele da Silva PintoAntônio Fernandes de CarvalhoÍtalo Tuler PerroneBovine milk and colostrum contain growth factors such as insulin-like growth factor IGF-I, IGF-II, transforming growth factor TGF-β1, TGF-β2, epidermal growth factor EGF, basic fibroblast growth factor bFGF and platelet-derived growth factor PDGF. In recent years, intense scientific interest has been focused on the identification of factors within bovine milk that may be relevant to improving human health. Then a number of methodologies for the extraction of milk growth factors from milk, colostrum or whey have been developed. Cation-exchange chromatography has been widely used because of the basic nature of the growth factors. Also, microfiltration has been used for the concentration of some growth factors from colostrum, while ultrafiltration was successful only in separating IGF-I from IGF-II in whey. Growth factor extracts from milk, colostrum or whey have been used as therapeutic preparations for wound healing and in the treatment of inflammatory gut disorders.https://www.revistadoilct.com.br/rilct/article/view/384Fatores de crescimentoseparaçãoquantificaçãotécnicas de membranacromatografia de troca catiônica. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fernanda Lopes da Silva Michele da Silva Pinto Antônio Fernandes de Carvalho Ítalo Tuler Perrone |
spellingShingle |
Fernanda Lopes da Silva Michele da Silva Pinto Antônio Fernandes de Carvalho Ítalo Tuler Perrone Transforming growth factor beta (TGF-β) in milk: a review Revista do Instituto de Latícinios Cândido Tostes Fatores de crescimento separação quantificação técnicas de membrana cromatografia de troca catiônica. |
author_facet |
Fernanda Lopes da Silva Michele da Silva Pinto Antônio Fernandes de Carvalho Ítalo Tuler Perrone |
author_sort |
Fernanda Lopes da Silva |
title |
Transforming growth factor beta (TGF-β) in milk: a review |
title_short |
Transforming growth factor beta (TGF-β) in milk: a review |
title_full |
Transforming growth factor beta (TGF-β) in milk: a review |
title_fullStr |
Transforming growth factor beta (TGF-β) in milk: a review |
title_full_unstemmed |
Transforming growth factor beta (TGF-β) in milk: a review |
title_sort |
transforming growth factor beta (tgf-β) in milk: a review |
publisher |
Empresa de Pesquisa Agropecuária de Minas Gerais (EPAMIG) |
series |
Revista do Instituto de Latícinios Cândido Tostes |
issn |
0100-3674 2238-6416 |
publishDate |
2016-06-01 |
description |
Bovine milk and colostrum contain growth factors such as insulin-like growth factor IGF-I, IGF-II, transforming growth factor TGF-β1, TGF-β2, epidermal growth factor EGF, basic fibroblast growth factor bFGF and platelet-derived growth factor PDGF. In recent years, intense scientific interest has been focused on the identification of factors within bovine milk that may be relevant to improving human health. Then a number of methodologies for the extraction of milk growth factors from milk, colostrum or whey have been developed. Cation-exchange chromatography has been widely used because of the basic nature of the growth factors. Also, microfiltration has been used for the concentration of some growth factors from colostrum, while ultrafiltration was successful only in separating IGF-I from IGF-II in whey. Growth factor extracts from milk, colostrum or whey have been used as therapeutic preparations for wound healing and in the treatment of inflammatory gut disorders. |
topic |
Fatores de crescimento separação quantificação técnicas de membrana cromatografia de troca catiônica. |
url |
https://www.revistadoilct.com.br/rilct/article/view/384 |
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