Sodium selenide toxicity is mediated by O2-dependent DNA breaks.

Hydrogen selenide is a recurrent metabolite of selenium compounds. However, few experiments studied the direct link between this toxic agent and cell death. To address this question, we first screened a systematic collection of Saccharomyces cerevisiae haploid knockout strains for sensitivity to sod...

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Bibliographic Details
Main Authors: Gérald Peyroche, Cosmin Saveanu, Marc Dauplais, Myriam Lazard, François Beuneu, Laurence Decourty, Christophe Malabat, Alain Jacquier, Sylvain Blanquet, Pierre Plateau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22586468/?tool=EBI