Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites

Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites

Abstract Background The Plasmodium genus of malaria parasites encodes several families of antigen-encoding genes. These genes tend to be hyper-variable, highly recombinogenic and variantly expressed. The best-characterized family is the var genes, exclusively found in the Laveranian subgenus of mala...

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Bibliographic Details
Main Authors: Hunter L. Gage, Catherine J. Merrick
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Genomics
Subjects:
Plasmodium
Laverania
Malaria
G quadruplex
var genes
pir genes
Online Access:http://link.springer.com/article/10.1186/s12864-020-6625-x

Internet

http://link.springer.com/article/10.1186/s12864-020-6625-x

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