Acetylation of PAMAM dendrimers for cellular delivery of siRNA

<p>Abstract</p> <p>Background</p> <p>The advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modi...

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Bibliographic Details
Main Authors: Uhrich Kathryn E, Sparks Sarah M, Waite Carolyn L, Roth Charles M
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/9/38