Interleukin-4-Mediated Oxidative Stress is Harmful to Hippocampal Neurons of Prothrombin Kringle-2-Lesioned Rat In Vivo

The present study investigated the effects of reactive microglia/macrophages-derived interleukin-4 (IL-4) on hippocampal neurons in prothrombin kringle-2 (pKr-2)-lesioned rats. pKr-2 was unilaterally injected into hippocampus in the absence or presence of IL-4 neutralizing antibody (IL-4Nab). Immuno...

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Bibliographic Details
Main Authors: Young Cheul Chung, Jae Yeong Jeong, Byung Kwan Jin
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/11/1068