Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels.

Scorpion toxins are important pharmacological tools for probing the physiological roles of ion channels which are involved in many physiological processes and as such have significant therapeutic potential. The discovery of new scorpion toxins with different specificities and affinities is needed to...

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Bibliographic Details
Main Authors: Rym ElFessi-Magouri, Steve Peigneur, Houcemeddine Othman, Najet Srairi-Abid, Mohamed ElAyeb, Jan Tytgat, Riadh Kharrat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4580410?pdf=render