The roles of APOBEC3G complexes in the incorporation of APOBEC3G into HIV-1.

The incorporation of human APOBEC3G (hA3G) into HIV is required for exerting its antiviral activity, therefore the mechanism underlying hA3G virion encapsidation has been investigated extensively. hA3G was shown to form low-molecular-mass (LMM) and high-molecular-mass (HMM) complexes. The function o...

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Bibliographic Details
Main Authors: Jing Ma, Xiaoyu Li, Jian Xu, Quan Zhang, Zhenlong Liu, Pingping Jia, Jinming Zhou, Fei Guo, Xuefu You, Liyan Yu, Lixun Zhao, Jiandong Jiang, Shan Cen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788789?pdf=render