Prenylflavonoids sanggenon C and kuwanon G from mulberry (Morus alba L.) as potent broad-spectrum bacterial β-glucuronidase inhibitors: Biological evaluation and molecular docking studies

Prenylflavonoids sanggenon C and kuwanon G from mulberry (Morus alba L.) as potent broad-spectrum bacterial β-glucuronidase inhibitors: Biological evaluation and molecular docking studies

Gut microbial β-glucuronidases show varied substrate specificity and inhibition propensity, highlighting the necessity of discovering broad-spectrum β-glucuronidase inhibitor to meet clinical needs. In this study, two prenylflavonoids sanggenon C (SGC) and kuwanon G (KWG) exhibited strong inhibition...

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Bibliographic Details
Main Authors: Bin Wei, Wei Yang, Zhi-Xiang Yan, Qing-Wen Zhang, Ru Yan
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Functional Foods
Subjects:
Sanggenon C
Kuwanon G
Human gut microbiota
β-Glucuronidase inhibitor
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618303487

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http://www.sciencedirect.com/science/article/pii/S1756464618303487

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