A Viral-Vectored Multi-Stage Malaria Vaccine Regimen With Protective and Transmission-Blocking Efficacies

A Viral-Vectored Multi-Stage Malaria Vaccine Regimen With Protective and Transmission-Blocking Efficacies

Malaria parasites undergo several stages in their complex lifecycle. To achieve reductions in both the individual disease burden and malaria transmission within communities, a multi-stage malaria vaccine with high effectiveness and durability is a more efficacious strategy compared with a single-sta...

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Bibliographic Details
Main Authors: Yenni Yusuf, Tatsuya Yoshii, Mitsuhiro Iyori, Hiroaki Mizukami, Shinya Fukumoto, Daisuke S. Yamamoto, Talha Bin Emran, Fitri Amelia, Ashekul Islam, Intan Syafira, Shigeto Yoshida
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
multi-stage malaria vaccine
transmission-blocking
Plasmodium falciparum circumsporozoite protein
Pfs25
human adenovirus serotype 5
adeno-associated virus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02412/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02412/full

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