Temporal Changes in Nucleus Morphology, Lamin A/C and Histone Methylation During Nanotopography-Induced Neuronal Differentiation of Stem Cells

Stem cell differentiation can be regulated by biophysical cues such as nanotopography. It involves sensing and integration of these biophysical cues into their transcriptome with a mechanism that is yet to be discovered. In addition to the cytoskeletal and focal adhesion remodeling, nanotopography h...

Full description

Bibliographic Details
Main Authors: Soneela Ankam, Benjamin K. K. Teo, Grace Pohan, Shawn W. L. Ho, Choon K. Lim, Evelyn K. F. Yim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2018.00069/full