IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.

IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.

In cancer patients pervasive systemic suppression of Dendritic Cell (DC) differentiation and maturation can hinder vaccination efficacy. In this study we have extensively characterized migratory DC subsets from human skin and studied how their migration and T cell-stimulatory abilities were affected...

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Bibliographic Details
Main Authors: Jelle J Lindenberg, Dinja Oosterhoff, Claudia C Sombroek, Sinéad M Lougheed, Erik Hooijberg, Anita G M Stam, Saskia J A M Santegoets, Henk J Tijssen, Jan Buter, Herbert M Pinedo, Alfons J M van den Eertwegh, Rik J Scheper, Hans J P M Koenen, Rieneke van de Ven, Tanja D de Gruijl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715492?pdf=render

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http://europepmc.org/articles/PMC3715492?pdf=render

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