TRPV1 Channels and Gastric Vagal Afferent Signalling in Lean and High Fat Diet Induced Obese Mice.

Within the gastrointestinal tract vagal afferents play a role in control of food intake and satiety signalling. Activation of mechanosensitive gastric vagal afferents induces satiety. However, gastric vagal afferent responses to mechanical stretch are reduced in high fat diet mice. Transient recepto...

Full description

Bibliographic Details
Main Authors: Stephen J Kentish, Claudine L Frisby, Stamatiki Kritas, Hui Li, George Hatzinikolas, Tracey A O'Donnell, Gary A Wittert, Amanda J Page
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4540489?pdf=render