RNA stimulates Aurora B kinase activity during mitosis.

Accurate chromosome segregation is essential for cell viability. The mitotic spindle is crucial for chromosome segregation, but much remains unknown about factors that regulate spindle assembly. Recent work implicates RNA in promoting proper spindle assembly independently of mRNA translation; howeve...

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Bibliographic Details
Main Authors: Ashwini Jambhekar, Amy B Emerman, Caterina T H Schweidenback, Michael D Blower
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4072698?pdf=render