Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib

Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib

Abstract Background Inhibition of metastasis of head and neck squamous cell carcinoma (HNSCC) is one of the most important challenges in cancer treatment. Src, a non-receptor tyrosine kinase, has been implicated as a key promoter in tumor progression and metastasis of HNSCC. However, Src therapy for...

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Bibliographic Details
Main Authors: Liwei Lang, Chloe Shay, Yuanping Xiong, Parth Thakkar, Ron Chemmalakuzhy, Xuli Wang, Yong Teng
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Hematology & Oncology
Subjects:
Src
Saracatinib
Nanoparticles
HNSCC
Metastasis
Online Access:http://link.springer.com/article/10.1186/s13045-018-0623-3

Internet

http://link.springer.com/article/10.1186/s13045-018-0623-3

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