Common Molecular Alterations in Canine Oligodendroglioma and Human Malignant Gliomas and Potential Novel Therapeutic Targets

Common Molecular Alterations in Canine Oligodendroglioma and Human Malignant Gliomas and Potential Novel Therapeutic Targets

Spontaneous canine (Canis lupus) oligodendroglioma (ODG) holds tremendous potential as an immunocompetent large animal model of human malignant gliomas (MG). However, the feasibility of utilizing this model in pre-clinical studies depends on a thorough understanding of the similarities and differenc...

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Bibliographic Details
Main Authors: Dana Mitchell, Sreenivasulu Chintala, Kaleigh Fetcko, Mario Henriquez, Brij N. Tewari, Atique Ahmed, R. Timothy Bentley, Mahua Dey
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Oncology
Subjects:
canine glioma
glioblastoma
molecular therapeutic targets
malignant glioma
anaplastic oligodendroglioma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00780/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00780/full

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