Rational Design of Hypoallergenic Vaccines: Blocking IgE-binding to Polcalcin Using Allergen-specific IgG Antibodies

Rational Design of Hypoallergenic Vaccines: Blocking IgE-binding to Polcalcin Using Allergen-specific IgG Antibodies

Chenopodium album polcalcin (Che a 3) is characterized as a major cause of cross-reactivity inallergic patients to the Chenopodiaceae family. Therefore, the present study was conducted to develop a hypoallergenic Che a 3 derivatives as the candidate vaccine for type 1 allergy. Four derivatives were...

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Bibliographic Details
Main Authors: Mohsen Mohammadi, Gholamreza Khamisipour, Faezeh Soltanpour, Fatemeh Omrani, Behrooz Taheri, Niloofar Momenzadeh, Moradali Fouladvand
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-06-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Chenopodium album
Immunotherapy
Polcalcin
Recombinant fusion proteins
Vaccine
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2552

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2552

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