A case of intraplacental gestational choriocarcinoma; characterised by the methylation pattern of the early placenta and an absence of driver mutations

A case of intraplacental gestational choriocarcinoma; characterised by the methylation pattern of the early placenta and an absence of driver mutations

Abstract Background Gestational choriocarcinoma is a rare malignancy believed to arise from the trophoblast cells of the placenta. Despite the frequently aggressive clinical nature, choriocarcinoma has been routinely curable with cytotoxic chemotherapy for over 50 years. To date little is known rega...

Full description

Bibliographic Details
Main Authors: Philip Savage, David Monk, Jose R. Hernandez Mora, Nick van der Westhuizen, Jennifer Rauw, Anna Tinker, Wendy Robinson, Qianqian Song, Michael J. Seckl, Rosemary A. Fisher
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Cancer
Subjects:
Oncogenesis
Trophoblast
Placenta
Choriocarcinoma
Methylation
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s12885-019-5906-8

Internet

http://link.springer.com/article/10.1186/s12885-019-5906-8

Similar Items