Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling
BDNF and its receptor TrkB regulate synaptic plasticity. TrkB triggers three downstream signaling pathways; Phosphatidylinositol 3-kinase (PI3K), Phospholipase Cγ (PLC γ) and Mitogen activated protein kinases/ Extracellular signal-regulated kinases (MAPK/ERK). We previously showed two distinct mecha...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-03-01
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Series: | Frontiers in Synaptic Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsyn.2014.00006/full |