Overexpression of lncRNA TUG1 Alleviates NLRP3 Inflammasome-Mediated Cardiomyocyte Pyroptosis Through Targeting the miR-186-5p/XIAP Axis in Coronary Microembolization-Induced Myocardial Damage

Overexpression of lncRNA TUG1 Alleviates NLRP3 Inflammasome-Mediated Cardiomyocyte Pyroptosis Through Targeting the miR-186-5p/XIAP Axis in Coronary Microembolization-Induced Myocardial Damage

Coronary microembolization (CME) is a complicated problem that commonly arises in the context of coronary angioplasty. The lncRNA taurine-up regulated gene 1 (TUG1), significantly contributes to cardiovascular diseases; however, its contribution to CME-induced myocardial damage remains elusive. Here...

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Bibliographic Details
Main Authors: You Zhou, Tao Li, Zhiqing Chen, Junwen Huang, Zhenbai Qin, Lang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
coronary microembolization
NLRP3 inflammasome
pyroptosis
lncRNA TUG1
miR-186-5p
XIAP
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.637598/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.637598/full

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