Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice[S]

Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice[S]

Low-grade inflammation in different tissues, including activation of the nuclear factor κB pathway in liver, is involved in metabolic disorders such as type 2 diabetes and cardiovascular diseases (CVDs). In this study, we investigated the relation between chronic hepatocyte-specific overexpression o...

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Bibliographic Details
Main Authors: Janna A. van Diepen, Man C. Wong, Bruno Guigas, Jasper Bos, Rinke Stienstra, Leanne Hodson, Steven E. Shoelson, Jimmy F.P. Berbée, Patrick C.N. Rensen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Journal of Lipid Research
Subjects:
nuclear factor kappa B
lipid metabolism
liver
very low density lipoprotein
IκB kinase β
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408806

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http://www.sciencedirect.com/science/article/pii/S0022227520408806

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