Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

Neuroinflammation is involved in the onset or progression of various neurodegenerative diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage-associated molecular patterns) and/or exogenous pathogens. Activation of glial cells (microglia and astrocytes) is widely rec...

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Bibliographic Details
Main Authors: Fuyuko Takata, Shinsuke Nakagawa, Junichi Matsumoto, Shinya Dohgu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
blood-brain barrier
pericyte
astrocyte
microglia
oligodendrocyte
tight junction
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.661838/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.661838/full

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