Maternal immunization with pneumococcal surface protein A protects against pneumococcal infections among derived offspring.

Pathogen-specific antibody plays an important role in protection against pneumococcal carriage and infections. However, neonates and infants exhibit impaired innate and adaptive immune responses, which result in their high susceptibility to pneumococci. To protect neonates and infants against pneumo...

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Bibliographic Details
Main Authors: Masamitsu Kono, Muneki Hotomi, Susan K Hollingshead, David E Briles, Noboru Yamanaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3205068?pdf=render