Effects of Bolus Injection of 5-Fluorouracil on Steady-State Plasma Concentrations of 5-Fluorouracil in Japanese Patients with Advanced Colorectal Cancer

<p><b>Objectives:</b> The irinotecan (CPT-11) + 5-fluorouracil (5-FU)/leucovorin (LV) + UFT/LV chemotherapy, in which repetitive oral administration of UFT/LV replaces the infusion of 5-FU/LV in the FOLFIRI regimen, has been proposed previously. In this study, five of 10 patients w...

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Bibliographic Details
Main Author: Takao Tamura, Akiko Kuwahara, Kaori Kadoyama, Motohiro Yamamori, Kohshi Nishiguchi, Tsubasa Inokuma, Yoshiji Takemoto, Naoko Chayahara, Tatsuya Okuno, Ikuya Miki, Yoshimi Fujishima, Toshiyuki Sakaeda
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v08p0406.htm