Genotype effects contribute to variation in longitudinal methylome patterns in older people

Genotype effects contribute to variation in longitudinal methylome patterns in older people

Abstract Background DNA methylation levels change along with age, but few studies have examined the variation in the rate of such changes between individuals. Methods We performed a longitudinal analysis to quantify the variation in the rate of change of DNA methylation between individuals using who...

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Bibliographic Details
Main Authors: Qian Zhang, Riccardo E Marioni, Matthew R Robinson, Jon Higham, Duncan Sproul, Naomi R Wray, Ian J Deary, Allan F McRae, Peter M Visscher
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Genome Medicine
Subjects:
DNA methylation
Longitudinal analysis
Methylation change
G by AGE
Online Access:http://link.springer.com/article/10.1186/s13073-018-0585-7

Internet

http://link.springer.com/article/10.1186/s13073-018-0585-7

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