Ablation of matrix metalloproteinase-9 prevents cardiomyocytes contractile dysfunction in diabetics

Ablation of matrix metalloproteinase-9 prevents cardiomyocytes contractile dysfunction in diabetics

Elevated expression and activity of matrix metalloproteinase-9 (MMP9) and decreased contractility of cardiomyocytes are documented in diabetic hearts. However, it is unclear whether MMP is involved in the regulation of contractility of cardiomyocytes in diabetic hearts. In the present study, we test...

Full description

Bibliographic Details
Main Authors: Priyanka ePrathipati, Naira eMetreveli, Shyam Sundar Nandi, Suresh Chand Tyagi, Paras Kumar eMishra
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Physiology
Subjects:
Diabetes Mellitus
Heart Failure
Calcium transient
Akita
Serca-2a
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00093/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00093/full

Similar Items