Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase.

Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase.

Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel therapeutic agents. Herein we report the promises of Dioscorea bulbifera and its bioactive principle, diosgenin as novel α-amylase...

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Bibliographic Details
Main Authors: Sougata Ghosh, Piyush More, Abhishek Derle, Ajay B Patil, Pramod Markad, Adersh Asok, Navanath Kumbhar, Mahemud L Shaikh, Boppana Ramanamurthy, Vaishali S Shinde, Dilip D Dhavale, Balu A Chopade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4162539?pdf=render

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http://europepmc.org/articles/PMC4162539?pdf=render

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