Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase.
Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel therapeutic agents. Herein we report the promises of Dioscorea bulbifera and its bioactive principle, diosgenin as novel α-amylase...
Main Authors: | Sougata Ghosh, Piyush More, Abhishek Derle, Ajay B Patil, Pramod Markad, Adersh Asok, Navanath Kumbhar, Mahemud L Shaikh, Boppana Ramanamurthy, Vaishali S Shinde, Dilip D Dhavale, Balu A Chopade |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4162539?pdf=render |
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