Identification of Key Genes in Purine Metabolism as Prognostic Biomarker for Hepatocellular Carcinoma

Identification of Key Genes in Purine Metabolism as Prognostic Biomarker for Hepatocellular Carcinoma

BackgroundDeregulated purine metabolism is critical for fast-growing tumor cells by providing nucleotide building blocks and cofactors. Importantly, purine antimetabolites belong to the earliest developed anticancer drugs and are still prescribed in clinics today. However, these antimetabolites can...

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Bibliographic Details
Main Authors: Wen-Jing Su, Pei-Zhi Lu, Yong Wu, Kumari Kalpana, Cheng-Kun Yang, Guo-Dong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
purine metabolism
bioinformatics
prognosis risk model
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.583053/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.583053/full

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