Intermittent hypoxia changes the interaction of the kinin–VEGF system and impairs myocardial angiogenesis in the hypertrophic heart

Intermittent hypoxia changes the interaction of the kinin–VEGF system and impairs myocardial angiogenesis in the hypertrophic heart

Abstract Intermittent hypoxia (IH) is a feature of obstructive sleep apnea (OSA), a condition highly associated with hypertension‐related cardiovascular diseases. Repeated episodes of IH contribute to imbalance of angiogenic growth factors in the hypertrophic heart, which is key in the progression o...

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Bibliographic Details
Main Authors: Bruna Visniauskas, Juliana C. Perry, Guiomar N. Gomes, Amanda Nogueira‐Pedro, Edgar J. Paredes‐Gamero, Sergio Tufik, Jair R. Chagas
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Physiological Reports
Subjects:
bradykinin receptors
carboxypeptidase M
hypertrophy
neovascularization
obstructive sleep apnea
preconditioning
Online Access:https://doi.org/10.14814/phy2.14863

Internet

https://doi.org/10.14814/phy2.14863

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