Ploidy dynamics increase the risk of liver cancer initiation

Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.

Bibliographic Details
Main Authors: Miryam Müller, Stephanie May, Thomas G. Bird
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21897-8