Identification of key genes involved in tumor immune cell infiltration and cetuximab resistance in colorectal cancer

Identification of key genes involved in tumor immune cell infiltration and cetuximab resistance in colorectal cancer

Abstract Background The anti-epidermal growth factor receptor (EGFR) antibody introduces adaptable variations to the transcriptome and triggers tumor immune infiltration, resulting in colorectal cancer (CRC) treatment resistance. We intended to identify genes that play essential roles in cetuximab r...

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Bibliographic Details
Main Authors: Li Liang, Mengling Liu, Xun Sun, Yitao Yuan, Ke Peng, Khalid Rashid, Yiyi Yu, Yuehong Cui, Yanjie Chen, Tianshu Liu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Drug resistance
Anti‐epidermal growth factor receptor therapy
Tumor immune cell infiltration
Transcriptional alterations
Online Access:https://doi.org/10.1186/s12935-021-01829-8

Internet

https://doi.org/10.1186/s12935-021-01829-8

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