Degradation of Tyrosinase by Melanosomal pH Change and a New Mechanism of Whitening with Propylparaben

Many active cosmetic ingredients formulated as medicated whitening products (quasi-drugs) achieve their effect through inhibition of tyrosinase activity, but no products can achieve this effect through degradation of intramelanosomal tyrosinase. Melanin is synthesized by tyrosinase, which is localiz...

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Bibliographic Details
Main Authors: Haifeng Zeng, Akane Harashima, Koichi Kato, Lihao Gu, Yosuke Motomura, Ryoichi Otsuka, Kazuhisa Maeda
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Cosmetics
Subjects:
pH
Online Access:https://www.mdpi.com/2079-9284/4/4/43