Maternal resistin predisposes offspring to hypothalamic inflammation and body weight gain.

Maternal resistin predisposes offspring to hypothalamic inflammation and body weight gain.

Resistin promotes hypothalamic neuroinflammation and insulin resistance through Toll like receptor 4 (TLR4), this hormone is thought to be a link between obesity and insulin-resistance. Indeed, resistin plasma levels are higher in obese and insulin resistant subjects. However, the impact of maternal...

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Bibliographic Details
Main Authors: Ghislaine Poizat, Coralie Alexandre, Sarah Al Rifai, Laure Riffault, Delphine Crepin, Yacir Benomar, Mohammed Taouis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213267

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https://doi.org/10.1371/journal.pone.0213267

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