Mechanistic Insight Into the Roles of Integrins in Osteoarthritis

Osteoarthritis (OA), one of the most common degenerative diseases, is characterized by progressive degeneration of the articular cartilage and subchondral bone, as well as the synovium. Integrins, comprising a family of heterodimeric transmembrane proteins containing α subunit and β subunit, play es...

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Bibliographic Details
Main Authors: Hongfu Jin, Shigang Jiang, Ruomei Wang, Yi Zhang, Jiangtao Dong, Yusheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.693484/full