NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications

NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications

Key features of chronic lymphocytic leukemia (CLL) are defects in the immune system and the ability of leukemic cells to evade immune defenses and induce immunosuppression, resulting in increased susceptibility to infections and disease progression. Several immune effectors are impaired in CLL, incl...

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Bibliographic Details
Main Authors: Paolo Sportoletti, Filomena De Falco, Beatrice Del Papa, Stefano Baldoni, Valerio Guarente, Andrea Marra, Erica Dorillo, Chiara Rompietti, Francesco Maria Adamo, Loredana Ruggeri, Mauro Di Ianni, Emanuela Rosati
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
chronic lymphocytic leukemia
NK cells
NK cell receptors
NK cell alterations
CLL immune evasion
NK cell-based immunotherapy
Online Access:https://www.mdpi.com/1422-0067/22/13/6665

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https://www.mdpi.com/1422-0067/22/13/6665

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