An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma

An Old Story Retold: Loss of G1 Control Defines A Distinct Genomic Subtype of Esophageal Squamous Cell Carcinoma

Esophageal squamous cell carcinoma (ESCC) has a high mortality rate. To determine the molecular basis of ESCC development, this study sought to identify characteristic genome-wide alterations in ESCC, including exonic mutations and structural alterations. The clinical implications of these genetic a...

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Bibliographic Details
Main Authors: Qiyan Wang, Jian Bai, Amir Abliz, Ying Liu, Kenan Gong, Jingjing Li, Wenjie Shi, Yaqi Pan, Fangfang Liu, Shujuan Lai, Haijun Yang, Changdong Lu, Lixin Zhang, Wei Chen, Ruiping Xu, Hong Cai, Yang Ke, Changqing Zeng
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Esophageal squamous cell carcinoma
Genomic subtype
Somatic mutation
Copy number alteration
Cell cycle deregulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022915001072

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http://www.sciencedirect.com/science/article/pii/S1672022915001072

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