Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells.

Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells.

The canonical Wnt/β-catenin pathway is constitutively activated in more than 90% of colorectal cancer (CRC) cases in which β-catenin contributes to CRC cell growth and survival. In contrast to the Wnt/β-catenin pathway, the non-canonical Wnt pathway can antagonize functions of the canonical Wnt/β-ca...

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Bibliographic Details
Main Authors: Tsui-Chin Huang, Pin-Tse Lee, Ming-Heng Wu, Chi-Chen Huang, Chiung-Yuan Ko, Yi-Chao Lee, Ding-Yen Lin, Ya-Wen Cheng, Kuen-Haur Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5578641?pdf=render

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http://europepmc.org/articles/PMC5578641?pdf=render

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