Wnt5a regulates midbrain dopaminergic axon growth and guidance.

During development, precise temporal and spatial gradients are responsible for guiding axons to their appropriate targets. Within the developing ventral midbrain (VM) the cues that guide dopaminergic (DA) axons to their forebrain targets remain to be fully elucidated. Wnts are morphogens that have b...

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Bibliographic Details
Main Authors: Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Malcolm K Horne, Maria L Macheda, Steven A Stacker, Ernest Arenas, Clare L Parish
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3069098?pdf=render