High interleukin-4 expression and interleukin-4 gene polymorphisms are associated with susceptibility to human paracoccidioidomycosis

High interleukin-4 expression and interleukin-4 gene polymorphisms are associated with susceptibility to human paracoccidioidomycosis

Paracoccidioidomycosis (PCM) is caused by dimorphic fungi from theParacoccidioides brasiliensis complex. Previous studies have demonstrated that the severity of disease is associated with a T-helper 2 immune response characterised by high interleukin (IL)-4 production. In the present study we analys...

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Bibliographic Details
Main Authors: Mônica Sawan Mendonça, Terezinha S Peraçolli, Mário León Silva-Vergara, Sílvio C Ribeiro, Rafael Faria Oliveira, Rinaldo Poncio Mendes, Virmondes Rodrigues Jr
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2015-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
gene polymorphism
IL-4
Paracoccidioides brasiliensis
paracoccidioidomycosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000600781&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000600781&lng=en&tlng=en

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