Effect of age and sex on immune checkpoint expression and kinetics in human T cells

Effect of age and sex on immune checkpoint expression and kinetics in human T cells

Abstract Background Immune checkpoints are crucial molecules in maintaining a proper immune balance. Even though age and sex are known to have effects on the immune system, the interplay between age, sex and immune checkpoint expression by T cells is not known. The aim of this study was to determine...

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Bibliographic Details
Main Authors: Rosanne D. Reitsema, Rebeca Hid Cadena, Sander H. Nijhof, Wayel H. Abdulahad, Minke G. Huitema, Davy Paap, Elisabeth Brouwer, Annemieke M. H. Boots, Peter Heeringa
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Immunity & Ageing
Subjects:
Immune checkpoints
Age
Sex
T cells
PD-1
CD40L
Online Access:http://link.springer.com/article/10.1186/s12979-020-00203-y

Internet

http://link.springer.com/article/10.1186/s12979-020-00203-y

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