PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1

PKCα Modulates Epithelial-to-Mesenchymal Transition and Invasiveness of Breast Cancer Cells Through ZEB1

ZEB1 is a master regulator of the Epithelial-to-Mesenchymal Transition (EMT) program. While extensive evidence confirmed the importance of ZEB1 as an EMT transcription factor that promotes tumor invasiveness and metastasis, little is known about its regulation. In this work, we screened for potentia...

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Bibliographic Details
Main Authors: María Candelaria Llorens, Fabiana Alejandra Rossi, Iris Alejandra García, Mariana Cooke, Martin C. Abba, Cynthia Lopez-Haber, Laura Barrio-Real, María Victoria Vaglienti, Mario Rossi, José Luis Bocco, Marcelo G. Kazanietz, Gastón Soria
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
epithelial-to-mesenchymal transition
EMT
metastasis
breast cancer
triple negative
TNBC
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01323/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01323/full

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