Comparison of commonly used methods in random effects meta-analysis: application to preclinical data in drug discovery research

Background Meta-analysis of preclinical data is used to evaluate the consistency of findings and to inform the design and conduct of future studies. Unlike clinical meta-analysis, preclinical data often involve many heterogeneous studies reporting outcomes from a small number of animals. Here, we re...

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Bibliographic Details
Main Authors: Tom van de Casteele, Malcolm R Macleod, Ezgi Tanriver-Ayder, Christel Faes
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:BMJ Open Science
Online Access:https://openscience.bmj.com/content/5/1/e100074.full