Whole Exome Sequence Analysis Provides Novel Insights into the Genetic Framework of Childhood-Onset Pulmonary Arterial Hypertension

Whole Exome Sequence Analysis Provides Novel Insights into the Genetic Framework of Childhood-Onset Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) describes a rare, progressive vascular disease caused by the obstruction of pulmonary arterioles, typically resulting in right heart failure. Whilst PAH most often manifests in adulthood, paediatric disease is considered to be a distinct entity with increased mo...

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Bibliographic Details
Main Authors: Simone M. Gelinas, Clare E. Benson, Mohammed A. Khan, Rolf M. F. Berger, Richard C. Trembath, Rajiv D. Machado, Laura Southgate
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Genes
Subjects:
exome sequencing
molecular genetics
lung disease
paediatrics
pulmonary arterial hypertension
Online Access:https://www.mdpi.com/2073-4425/11/11/1328

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https://www.mdpi.com/2073-4425/11/11/1328

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