Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes
20-Hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE), a product of the cytochrome P450 (CYP)-catalyzed ω-hydroxylation of arachidonic acid, induces oxidative stress and, in clinical studies, is associated with increased body mass index (BMI) and the metabolic syndrome. This study was designed to exa...
Main Authors: | Dong Hyun Kim, Nitin Puri, Komal Sodhi, John R. Falck, Nader G. Abraham, Joseph Shapiro, Michal L. Schwartzman |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2013-03-01
|
Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752041942X |
Similar Items
-
Role of Group X Secretory Phospholipase A<sub>2</sub> in Murine Adipocytes
by: Li, Xia
Published: (2010) -
Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes
by: Iva Kladnicka, et al.
Published: (2021-07-01) -
Recent Advances in Proteomic Studies of Adipose Tissues and Adipocytes
by: Eun Young Kim, et al.
Published: (2015-02-01) -
Characterization of Medullary and Human Mesenchymal Stem Cell-Derived Adipocytes
by: MacKay, Maria-Danielle L.
Published: (2009) -
The actin cytoskeleton during adipocyte formation
by: Torres, Lynes Judith
Published: (2016)